Epstein-Barr virus (EBV) is typically found in a latent, asymptomatic state in immunocompetent individuals. Perturbations of the host immune system can stimulate viral reactivation. Furthermore, there are a myriad of EBV-associated illnesses including various cancers, post-transplant lymphoproliferative disease, and autoimmune conditions. A thorough understanding of this virus, and the
Get a quoteMay 10, 2017 · This systematic approach uncovered key mechanisms by which EBV oncoproteins activate the PI3K/AKT pathway and evade tumor suppressor responses, and identifies viral transformation-driven synthetic lethal targets for therapeutic intervention. Epstein-Barr virus (EBV) causes endemic Burkitt lymphoma (BL) and immunosuppression-related lymphomas. These B cell …
Get a quoteHistone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation Oct 27, 2020 |
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Get a quoteHistone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. PubMed | mBio. Guo R, Zhang Y, Teng M, …, Cesarman E, Giulino-Roth L, Gewurz BE. (2020) DNA methylation enzymes and PRC1 restrict B-cell Epstein–Barr virus oncoprotein expression. PubMed | Nature Microbiology
Get a quoteNov 08, 2021 · Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. mBio. 2020; 11. doi: 10.1128/mBio.01063-20 33109754 18 Zhang K, Lv D-W, Li R. B Cell Receptor Activation and Chemical Induction Trigger Caspase-Mediated Cleavage of PIAS1 to Facilitate Epstein-Barr Virus Reactivation. Cell Rep. 2017; 21: 3445 – 3457.
Get a quote"Gene Expression Regulation, Viral" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.
Get a quoteOct 28, 2013 · Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. Zhang Y, Jiang C, Trudeau SJ, Narita Y, Zhao B, Teng M, Guo R, Gewurz BE. mBio, 11(5), 27 Oct 2020 Cited by: 3 articles | PMID: 33109754 | PMCID: PMC7593962. Free to read & use
Get a quoteEpstein-Barr virus (EBV) is a model of herpesvirus latency and epigenetic changes. The virus preferentially infects human B- the recruitment of histones supported by histone chaperones such as HIRA, DAXX, CAF1, ASF1, DEK, and several others, which can manage transport, location and deposition,
Get a quote7290 - Gene ResultHIRA histone cell cycle regulator [ (human)]
Get a quoteYear Citation Score; 2020: Li J, Shang Y, Wang L, Zhao B, Sun C, Li J, Liu S, Li C, Tang M, Meng FL, Zheng P. Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia. Science Advances.6. PMID 33115731 DOI: 10.1126/sciadv.aba0682 : 0.76: 2020: Zhao B, Sun LS, Chen J. Hybrid parity-time modulation phase and geometric phase in
Get a quoteMay 10, 2017 · This systematic approach uncovered key mechanisms by which EBV oncoproteins activate the PI3K/AKT pathway and evade tumor suppressor responses, and identifies viral transformation-driven synthetic lethal targets for therapeutic intervention. Epstein-Barr virus (EBV) causes endemic Burkitt lymphoma (BL) and immunosuppression-related lymphomas. These B cell …
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Get a quoteArticle Title: Histone loaders CAF1 and HIRA restrict Epstein-Barr virus B-cell lytic reactivation Article Snippet: 30 μl proteinase K (20 mg/ml, New England Biolabs, #P8107S) and 100 μl 10% (wt/vol) SDS (Invitrogen, #155553-035) were then were added to the reaction mixtures, which were incubated for 1 h at 65°C. ..DNA was purified by phenol-chloroform extraction followed by isopropanol
Get a quoteSep 18, 2021 · Epstein-Barr virus (EBV) is typically found in a latent, asymptomatic state in immunocompetent individuals. Perturbations of the host immune system can stimulate viral reactivation. Furthermore, there are a myriad of EBV-associated illnesses including various cancers, post-transplant lymphoproliferative disease, and autoimmune conditions. A thorough understanding of this virus, and …
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Get a quoteNov 08, 2021 · Zhang Y, Jiang C, Trudeau SJ, Narita Y, Zhao B, Teng M, et al. Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. mBio. 2020;11. pmid:33109754 . View Article PubMed/NCBI Google Scholar 18.
Get a quoteApr 28, 2020 · 18 Running title: Histone Loader CAF1 Restricts EBV Lytic Reactivation 19 ABSTRACT 20 Epstein-Barr virus (EBV) infects 95% of adults worldwide and causes infectious mononucleosis. 21 EBV is associated with endemic Burkitt lymphoma, Hodgkin lymphoma, post-transplant 22 lymphomas, nasopharyngeal and gastric carcinomas.
Get a quoteNov 12, 2008 · Histone Loaders CAF1 and HIRA Restrict Epstein-Barr Virus B-Cell Lytic Reactivation. Zhang Y, Jiang C, Trudeau SJ, Narita Y, Zhao B, Teng M, Guo R, Gewurz BE. mBio, 11(5), 27 Oct 2020 Cited by: 3 articles | PMID: 33109754 | PMCID: PMC7593962. Free to read & use
Get a quoteMar 01, 2010 · Epstein–Barr virus lytic replication elicits ATM checkpoint signal transduction while providing an S-phase-like cellular environment. J. Biol. Chem., 280 (2005), pp. 8156-8163. Histone loaders caf1 and hira restrict epstein-barr virus b-cell lytic reactivation. 2020, mBio.
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